The following drug updates are not found in the current version of these booklets, as these treatments were not FDA approved at the time the books were published.
- In November 2025, the Food and Drug Administration (FDA) expanded the indication of daratumumab and hyaluronidase-fihj (Darzalex Faspro®)to include the treatment of high-risk smoldering multiple myeloma as monotherapy.
- In November 2025, the Food and Drug Administration (FDA) updated the indication of belantamab mafodotin-blmf (Blenrep) in combination with bortezomib and dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least two prior lines of therapy, including a proteasome inhibitor and an immunomodulatory agent.
- In July 2025, the Food and Drug Administration (FDA) approved linvoseltamab-gcpt (Lynozyfic™) for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.
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