Skip to main content

Myeloproliferative neoplasms (MPNs)

What are myeloproliferative neoplasms (MPNs)?

Myeloproliferative neoplasms (MPNs) are types of blood cancer that begin with an abnormal mutation (change) in a stem cell in the bone marrow, the spongy tissue inside the large bones of the body. The mutation leads to an overproduction of any combination of white cells, red cells, and platelets.  

  • “Myelo” refers to bone marrow
  • “Proliferative” means to grow or reproduce quickly
  • “Neoplasm” is an abnormal growth of cells  

There are several types of MPNs. Each type affects different blood cells and has specific criteria for its diagnosis. Some MPNs are slow growing or “indolent”; others are more aggressive. 

Knowing more about the different types of MPNs can help you feel more prepared when discussing options with your doctors.

Learn more about the different types of MPNs:

Blood Cancer United resources

Find free, specialized guidance and information for every type of blood cancer, request financial support, find emotional support, and connect with other members of the blood cancer community.

We are Blood Cancer United.

Everyone affected by blood cancer—patients, survivors, caregivers, researchers, advocates, fundraisers, everyone—has a story. Share yours.
Andrew Rich running at the racing event, Team in Training paticipant

Team In Training Participant

Team In Training Participant

Alaska LFA Zip Code List

Sandy

Supporter

Volunteer

Volunteer

Lynette

Volunteer

Michele

Volunteer

Kathie & Dave

Supporters

Smiling woman holding #supporter sign next to lamp with red light

Monica

Volunteer

Glenn, blood cancer survivor, seated at table with two companions

Glenn

Survivor

Rafael

Scientist

Smiling woman in flower shirt  sitting on white chair

Lauren

Leukemia Patient

George, volunteer, wearing George Thorogood and The Destroyers' Good To Be Bad Tour t-shirt

George

Volunteer

LLS Researchers

LLS Global Research

The Leukemia & Lymphoma Society (LLS) is now Blood Cancer United. Learn more.