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Nancy
My first diagnosis was in when I got the news I had stage lymphoma. I went through chemo and radiation for this. years later I was diagnosed again …
Stories
Targeting Myeloid Malignancies through IRAK4 Synthetic Lethality Dependencies
Based on our preliminary data, we hypothesize that IRAK4 inhibition leads to LSPC reprogramming in MDS and AML. Aim will evaluate the mechanism by wh…
Autologous stem cell transplantation
In autologous stem cell transplantation, the procedure uses the patient’s own stem cells for the transplant. The stem cells are collected from the pat…
Support Resources
Autologous stem cell transplantation for children and teens
In autologous stem cell transplantation, the procedure uses the patient’s own stem cells for the transplant. The stem cells are collected from the pat…
Support Resources
Autologous stem cell transplantation for young adults
In autologous stem cell transplantation, the procedure uses the patient’s own stem cells for the transplant. The stem cells are collected from the pat…
Support Resources
LCK-targeted Therapy in T cell Acute Lymphoblastic Leukemia
acute lymphoblastic leukemia () is a highly aggressive leukemia in adults with -year survival rate of only about % in patients with relapsed/refractor…
The Andrew McDonough B+ Foundation
The Andrew McDonough B+ Foundation has four areas of focus: financial assistance, childhood cancer research, awareness and spreading positivity …
Relevance of ubiquitin dependent proteolysis in diffuse large B-cell lymphoma
The goal of this proposal is to investigate the significance of genes of the ubiquitin proteasome system (UPS) that are mutated in Diffuse Large Lymp…
Impact of Health Insurance on Mortality for Children and AYAs Newly Diagnosed with a Blood Cancer: A Population-Based Multistate Evaluation
Lacking continuous insurance is a key barrier to access to timely care. This study will provide the first evidence of whether insurance continuity pro…
Inflammation-responsive mechanisms of malignant stem cell generation and eradication in multiple myeloma
The focus of my research is to elucidate the core molecular regulators of malignant stem cell generation in multiple myeloma. My approach addresses th…
Metabolic Regulation of Leukemic Cell Fate
metabolic processes are dysregulated in acute myeloid leukemia (AML) and can act to sustain an oncogenic state of differentiation arrest. Using AML ce…
Identifying novel regulators of leukemic progression in GATA2-deficiency syndrome
GATA2 deficiency is an inherited pediatric syndrome with a high rate of progression to myeloid malignancy, the mechanisms of which remain largely unde…
Modeling LSC heterogeneity at unprecedented resolution in AML
Our goal is to perform molecular characterization of human leukemia stem cells (LSCs). We have developed an integrated set of techniques that will a…
Targeting Microenvironment Determinants in Peripheral T-cell Lymphoma
Peripheral lymphomas are highly aggressive blood cancer that have very poor survival rate, highlighting the need for new therapies to improve patient…
Suggested Reading - Henry and the White Wolf
Written and illustrated by a teenage brother and sister, this is an allegory about a sick hedgehog that is healed by the feared white wolf. Geared to …
Keri
In the Summer of , I started losing weight. As an avid CrossFit athlete, I thought it was from working hard in the gym. Next came fatigue; I just thou…
Carlos
In March , I went through something I hoped would be my final battle with cancer — an autologous stem cell transplant after being diagnosed with stage…
Will
My son Will was a vibrant, active, and typical junior in high school. He was living life to the fullest with a rigorous class schedule, working, train…
Dare 2 Dream
Cynthia
In June , I dislocated my knee. I saw the doctor and after an MRI and an was told I needed physical therapy and rest. I did both and my knee saw a sl…
Dominick
My grandson, Dominick, was diagnosed with acute lymphoblastic leukemia (ALL) in November . He was / years old and it was only eight months after hi…
Michael
In April , I was diagnosed with stage peripheral lymphoma (PTCL). I enrolled in a phase clinical trial through VCU Massey Cancer Center. After the …
Stories
Tony
It was years ago that Tony was diagnosed with acute lymphoblastic leukemia (ALL) at age . Back then, the disease wasn't very well understood, and the…
Janie
My name is Janie, and I was diagnosed with acute myeloid leukemia (AML) almost one year ago at years old. I am married with two children and am so ha…
Dare 2 Dream
Isabel
My journey began unexpectedly when I was diagnosed with Hodgkin lymphoma (HL) at just seven weeks pregnant. It all started with what I thought was the…
Alana
My name is Alana, and I’m years old. Here is my story. On June , , I was out having dinner with my family, and my smartwatch told me that my heart ra…