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Paul is
Blood Cancer United

My husband's story began in July 2018, when he suddenly became ill. I rushed him to the ER. The shocking diagnosis, multiple myeloma. Three weeks prior to his hospitalization he had a physical with blood work, all was normal.

He fought a tough battle from July 2018 with three hospitalizations, which included an ICU hospital stay, a rehab and a sub-acute rehab to learn to to walk. Miraculously, he came home in November 2018. From November 2018, he was on various chemo treatments that worked and eventually, didn't work. Then, September 2019, he had a long awaited stem cell transplant. In Dec 2019, we found out that the stem cell transplant was not successful.

In, January 2020, we started looking at clinical trials and appointments with multiple myeloma specialty doctors out of state. Paul continued on other several new chemo regiments and 5 rounds of radiation to his head area between February 2020 until August 2020. Paul was then scheduled for a clinical trial drug twice, which unfortunately fell through. Then, in September 2020 Paul was scheduled for one round of a different chemo and rescheduled for a long awaited clinical trial drug.

Unfortunately, Paul did not make it. Paul Mancuso, 50, of Wallingford, died suddenly from other complications on Monday, September 7, 2020. He was the beloved husband of Karen (Jones) Mancuso, and devoted father of Michael Mancuso. He was born in Bridgeport, January 9, 1970, the son of Domenic Mancuso of Florida and the late Susan (Colandrea) Mancuso and was a Graduate of Bunnell High School. Paul was fighting a courageous three year battle with multiple myeloma, he was in active treatment and scheduled for a promising clinical trial drug at SK NY. He was employed before his illness by Car Quest in Milford and Autopart International in North Haven. Paul was an avid fan of baseball (Boston Red Sox), hockey (NJ Devils), Nascar, and football (Denver Broncos), chopping wood, and computer gaming with his special group of online friends, and he loved fishing.

He enjoyed backyard grilling and spending time with his family and friends, traveling, and his famous pen collection. He was a family man who had an infectious personality that was larger than life itself, excellent work ethic, sense of humor and a smile that could brighten anyone's day, a huge heart, and he would help anyone out in a heartbeat. His pride and joy, heart and soul was his son Michael (who was named after one of his favorite uncles, Uncle Mike). In addition to his wife Karen, his son Michael, and his father Domenic of Florida. He is also survived by his sister and brother-in-law, Cathy and Gabe Gaudio of Florida; his brother and sister-in-law, Chris and Kathy Mancuso and her daughter Julianna of Naugatuck; his nieces, Cathy Hoffman and her husband Chris, and Julie Provonsil and her husband Mat; his great niece Chelsea Hoffman all of Florida; his special aunt and uncle William and Gloria Paul, several cousins, special cousins and family members who helped him through his health struggle: John Paul and his wife Heather, William Paul Jr., William Davidson Jr., Judy Pester, Frank Rossi, Violet Lajoie, and Al Bodnar; and his beloved dog, Salvatore. And several friends and devoted friends who were by his side: Robert and Cathleen, John and Damaris, Scott and Lauren, Drew, Mark, Dan and Jen, Sandy and Stu, Martin and Renee.

Paul was predeceased by several aunts, uncles, and cousins, as well as his mother in law Marlene Lajoie-Jones. The family would like to deeply thank those who cared for him the last three years for his multiple myeloma - Dr. Gerard Fumo, Nathan St. Louis APRN, and the entire oncology nursing department and staff at Midstate Medical Center (who saved his life in 2018), Dr. Noffar Bar and Paul's favorite nurses and the staff at Smilow North Haven. Paul may physically be gone, but his life left an everlasting imprint in the hearts and minds on those who met him.

Paul

In Memory

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Everyone affected by blood cancer—patients, survivors, caregivers, researchers, advocates, fundraisers, everyone—has a story. Share yours.
Copilot said: Person stands outdoors holding an illuminated lantern at a Light The Night event, with a large screen in the background showing participants raising lights and the message “Thank you for bringing light to the darkness of cancer,” highlighting advocacy, community support, and awareness in the blood cancer community.

Natalia

splenic marginal zone non-Hodgkin lymphoma (MZL)

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Zeke

acute lymphoblastic leukemia (B-ALL)

Lila wearing warm clothes-standing in front of a 'top of Mt. Kilimanjaro' sign with arms raised

Lila

acute myeloid leukemia (AML)

Snapshot of Ashley wearing black jacket with Find the Cure printed, a cancer survivor

Ashley

chronic myelogenous leukemia (CML)

Snapshot of Zachariah holding flowers, a cancer survivor

Zach

Hodgkin lymphoma (HL)

A person is seated in a medical treatment chair with an IV line connected to the arm. The individual is wearing a tie-dye sweatshirt and has a blue protective sheet draped over the lap. A patterned blanket covers part of the legs, and a white disposable cup is placed on a small tray nearby. In the background, there is medical equipment including an infusion pump with digital displays, tubing, and a yellow biohazard container. The setting appears to be a clinical or hospital environment.

Natalie

Hodgkin lymphoma (HL)

Rachel in hospital with head wrap holding "It's my last day of chemo" sign

Rachel

lymphoma

Rebecca young adult in hospital chair holding shirt "Fighting Together With You"

Rebecca

blood cancer

Richard in a chair outside with a Corona smiling in a blue hooded jacket

Richard

In memory

JJ standing among leaves gazing into the distance

J.J.

Volunteer

Brianna, close up and smiling, young adult survivor of childhood cancer

Brianna

acute lymphoblastic leukemia (ALL)

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Henry Jr

leukemia

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