1630 results for Leukemia

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Edward Jones & The Leukemia & Lymphoma Society

Invest in a Future Without Cancer The Leukemia & Lymphoma Society (LLS) is excited to partner with Edward Jones to provide unmatched opportunities fo…

Chronic Lymphocytic Leukemia 3D Model

Chronic Lymphocytic Leukemia 3D Model

This model contains the following chapters. Click the "Interact in 3D" button to begin.Healthy Bone MarrowNormal Blood Cell ProductionProliferation of…

3D Models

Supporting allogeneic CD371 (CLL-1) CAR development for acute myeloid leukemia

In February 2021, LLS made an equity investment in Caribou Biosciences to "Support allogeneic CD371 (CLL-1) CAR development for acute myeloid leukemia…

Suggested Reading - Childhood Leukemia Guide for Families, Friends and Caregivers, 5th ed.

Suggested Reading - Childhood Leukemia Guide for Families, Friends and Caregivers, 5th ed.

By Nancy Keene Childhood Cancer Guides, 2018, 496 pages ISBN: 978-1-941089-04-0 This most complete parent guide provides accurate and understanda…

BRAF inhibition as an alternative to chemotherapy in the treatment strategy of hairy cell leukemia

Hairy cell leukemia (HCL) is very sensitive to chemotherapy, whose toxicity to the bone marrow and the immune system is however concerning. We have es…

Dissecting the heterogeneity of leukemic and pre-leukemic clonal expansion to identify genes associated with leukemia relapse and genesis

My research investigates the heterogeneity of leukemic and pre-leukemic clonal expansion to identify genes associated with leukemia relapse and genesi…

Interrogation of glutathione biology in relapsed acute myeloid leukemia stem cells

Acute myeloid leukemia (AML) is a devastating blood cancer. Most AML patients will initially respond to standard therapy; however, for many patients t…

Identification of therapeutic targets sensitizing acute myeloid leukemia to BCL2 inhibitors

Venetoclax is a medication that can induce cell death of acute myeloid leukemia (AML), but its effectiveness needs to be further improved to benefit m…

Improving the outcomes of young Black adults diagnosed with acute myeloid leukemia

Young Black patients diagnosed with acute myeloid leukemia (AML) have significantly shorter survival compared to White patients. To comprehensively as…

A phase 1b/2 study targeting apoptotic and signaling pathways in T-acute lymphoblastic leukemia

T-acute lymphoblastic leukemia (T-ALL) is an aggressive leukemia with limited treatment options after first-line chemotherapy. Our preclinical work in…

The Leukemia & Lymphoma Society 2025 Research Grants Include Acute Leukemia in Children with Down Syndrome

The Leukemia & Lymphoma Society 2025 Research Grants Include Acute Leukemia in Children with Down Syndrome

LLS has more than $250 million research funding commitments to propel the next generation of blood cancer care Patient education, financial support an…

News Release

Improving BTK Inhibitor Therapy in Chronic Lymphocytic Leukemia Through Rational Combination Strategies

Ibrutinib is a targeted oral treatment for CLL that is safe and highly effective, however it must be given indefinitely which leads to chronic side ef…

Modeling the Initiation and Progression of Down Syndrome Associated Leukemia using CRISPR/Cas9 at Single Cell Resolution

Children with Down syndrome (Trisomy 21) have an increased risk of childhood leukemia and, in these cases, the initiating genetic alterations already …

Suggested Reading -Cancer Crossings: A Brother, His Doctors, and the Quest for a Cure to Childhood Leukemia

Suggested Reading -Cancer Crossings: A Brother, His Doctors, and the Quest for a Cure to Childhood Leukemia

Cancer Crossings: A Brother, His Doctors, and the Quest for a Cure to Childhood Leukemia by Tim WendelILR Press, 2018, 256 Pages, Paperback and Kindle…

Therapeutic targeting of T-cell acute lymphoblastic leukemia using an AKR1C3-activated prodrug

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy that is exceptionally difficult to cure after relapse. We have previously show…

Precision Targeting of Hairy Cell Leukemia using Chimeric Antigen Receptor T cells

<p>Though effective treatments in hairy cell leukemia and variant (HCLv) exist, they are associated with profound immunosuppression; thus, more …

Targeting kinase-dependent dysregulation of transcription factor control in acute myeloid leukemia

Defining mechanisms of dysregulated gene control are central to understanding cancer and the development of effective therapies. Our research is focus…

Immunotherapy Study Funded by The Leukemia & Lymphoma Society Demonstrates Remarkable Results in Patients with Acute Lymphoblastic Leukemia

Immunotherapy Study Funded by The Leukemia & Lymphoma Society Demonstrates Remarkable Results in Patients with Acute Lymphoblastic Leukemia

Contact: Andrea Greif(914) [email protected] Plains, NY (October 16, 2014) - Funding from The Leukemia & Lymphoma Society (LLS) over t…

News Release

Leukemia Research Funded by The Leukemia & Lymphoma Society Gets Infusion of Support from Startup Biotechnology Company

White Plains, NY - March 30, 2015 - A promising University of Michigan research project focused on developing new treatments for patients with a rare …

News Release

FDA Approves Vyxeos for Secondary Acute Myeloid Leukemia in Children

DUBLIN, March 30, 2021 - Jazz Pharmaceuticals plc (Nasdaq: JAZZ) announced that the U.S. Food and Drug Administration (FDA) approved a revised label f…

Pharmacological inhibition of the transcription factor PU.1 as a novel treatment for acute myeloid leukemia

Transcription factors are components of a cell which control our genetic information and are known to have altered function in diseases such as Acute …

Pluripotent Stem Cell-derived CAR-T and CAR-NK Cells for Immunotherapy of Leukemia and Lymphoma

Cytotoxic cells of the immune system, including T and NK cells, can be targeted to seek out and destroy leukemia, lymphoma and myeloma cells by engine…

Breakthroughs and Progress: Acute Myeloid Leukemia (AML)

Breakthroughs and Progress: Acute Myeloid Leukemia (AML)

Topics CoveredWe invite you to learn more about:Treatment options for AMLStrategies to manage side effectsNew therapies being studied for AMLDiscussin…

Education Resources

Highlights In Therapy For Chronic Lymphocytic Leukemia (CLL)

Highlights In Therapy For Chronic Lymphocytic Leukemia (CLL)

Topics CoveredWe invite you to learn more about:Treatments for CLLMonitoring and managing side effectsStrategies to improve quality of life …

News Release