1353 results for Leukemia
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Targeting the pathogenic 'fire triangle' of inflammation, metabolism and mutations in myeloid leukemogenesis
My lab is focused on understanding the pathogenic interplay between oncogenic mutations, chronic inflammation and aberrant metabolism as a driver of t…
Suggested Reading - CAR T-Cell Therapy: What to Expect
CAR therapy is an exciting new treatment currently approved by the U. S. Food and Drug Administration for patients with certain types of lymphoma or …
Suggested Reading - Samson's Tale
Samson's Tale is a wonderfully written and warmly illustrated picture book that tells the story of a young boy with leukemia from his pet perspective.…
Liz
In December , I was diagnosed with acute myeloid leukemia (AML). I had just finished finals and had not been feeling well, so I went to the doctor whe…
Dare 2 Dream
Stories
Michelle
I want to take a minute to thank everyone who supported me during my leukemia journey. It’s been almost years. On December , , I was diagnosed with c…
Ashley
I grew up hearing stories about when my uncle Mark was diagnosed with leukemia. The heartache, the stress on the family, the fear and luckily for all…
Pam
I was diagnosed with myelodysplastic syndrome (MDS) in December of . I went through six treatments from January to June . The treatments were a serie…
Bishoy
Born in Egypt, at the age of three, me and my family immigrated to the U.S. when I was diagnosed with acute lymphoblastic leukemia (ALL). I grew up in…
Jim
My brother Jim was an amazing man. He was a person for whom family was everything. He ran a plumbing business with his brothers and took pride in its …
John
I first got involved with The Leukemia & Lymphoma Society (LLS) shortly after the passing of my boyfriend, John, in . John "Poochy" fought a very long…
Immune-Onc Therapeutics
In , LLS made an equity investment in Therapeutics. is a cancer immunotherapy company dedicated to the discovery and development of novel myeloid c…
Nathaniel
In at just months old, Nathaniel started to get sick on a regular basis. He started running a fever and his blood count was really low and we pushed…
Charlene
Cancer. That is a word that is scary. So many of us have friends, family and that are impacted by some type of cancer, but you never think it will be…
Babara
On October , , I was diagnosed with chronic myeloid leukemia (CML) at the age of . I was asymptomatic, so I was in total denial that I had leukemia. I…
Targeting SF3B1 splicing factor mutant myeloid malignancies through dependency on GPATCH8
Mutations in RNA splicing factors, particularly those involving the core splicing factor SF3B1 are amongst the most common mutations found in myeloid …
Novel targeted therapies for acute myeloid leukaemia and multiple myeloma
Outcomes for acute myeloid leukemia (AML) and multiple myeloma (MM) patients remain inadequate and new treatment options to combat resistance against …
Uncovering MGA-driven epigenetic reprogramming in Richter's syndrome
Richter’s syndrome (RS) is a critical complication of chronic lymphocytic leukemia. RS patients are refractory to most existing therapies and show a m…
Research: Grants
CLL Patient Databases
Maintains information on a large number of patients with chronic lymphocytic leukemia to contribute to medical research about its diagnosis, prognosis…
MPN Education Foundation
To bring education, information and emotional support to MPN patients; to increase awareness amongst patients, physicians and caregivers of myeloproli…
Acosta
In my son was diagnosed with leukemia at the age of and after yrs of chemotherapy he’s finally cured. In I was diagnosed with lymphoma stage .…
Mantle Cell Lymphoma Video Vignettes for Healthcare Professionals
Developed through a collaboration between The Leukemia & Lymphoma Society & The Association of Cancer Care Centers.This video series provides an overv…
Education Resources
Impaired dynamic nucleosome remodeling as a leukemogenic mechanism and therapeutic target in AML
The cohesin and BAF complexes are both epigenetic regulators of dynamic chromatin accessibility. Recurrent mutations are observed in proteins of both …
Kacy
I am on this adventure to help others and challenge myself! I do not have a personal story or relationship with The Leukemia & Lymphoma Society (LLS),…
Metabolic Regulation of Leukemic Cell Fate
metabolic processes are dysregulated in acute myeloid leukemia (AML) and can act to sustain an oncogenic state of differentiation arrest. Using AML ce…
Mechanisms of Clonal Evolution in the Transformation of MPN to sAML
This research will investigate blood stem cell mutations associated with progression of myeloproliferative neoplasm (MPN) to secondary acute myeloid l…