Skip to main content

Polycythemia vera (PV) develops slowly, and it may not cause symptoms for many years. The condition is often diagnosed during a routine blood test before severe symptoms occur. Reduced blood flow due to high numbers of red blood cells and the enlargement of the spleen are what cause a patient’s symptoms. 

Signs and symptoms of PV 

  • Fatigue
  • Pruritus (itchy skin), especially after warm baths or showers
  • Redness, pain and burning feeling on the skin of the face, hands, or feet (erythromelalgia)
  • Headaches, dizziness and weakness
  • Difficulties concentrating
  • Night sweats
  • Insomnia
  • Blurred vision, double vision, or seeing dark or blind spots that come and go
  • Ringing in the ears (tinnitus)
  • Shortness of breath
  • Angina (chest pain)
  • Weakness
  • Dizziness
  • Excessive bleeding or bruising
  • Peripheral neuropathy (numbness, tingling or burning sensation in the feet)
  • Swelling and pain in the stomach
  • Feeling full after eating small amounts of food
  • Weight loss for no known reason
  • Bone pain, most often the legs  

When PV causes symptoms, they can be troublesome. Reducing symptoms is a key goal of treatment. Therefore, it is important to take an active role in monitoring your PV symptoms. 

 Careful tracking of your symptoms can help you and your doctor better understand how to manage and modify your care over time.

Get free, one-on-one support

Call, email, or chat with a member of our highly trained support team.

Blood Cancer United resources

Find free, specialized guidance and information for every type of blood cancer, request financial support, find emotional support, and connect with other members of the blood cancer community.

We are Blood Cancer United.

Everyone affected by blood cancer—patients, survivors, caregivers, researchers, advocates, fundraisers, everyone—has a story. Share yours.
Alaska LFA Zip Code List

Sandy

Supporter

Lynette

Volunteer

Kathie & Dave

Supporters

Glenn, blood cancer survivor, seated at table with two companions

Glenn

Survivor

Smiling woman in flower shirt  sitting on white chair

Lauren

Leukemia Patient

LLS Researchers

LLS Global Research

A young, Nick, standing on stage with his parent receiving a giant donation check

Nick

LLS Volunteer

Portrait of Jason, volunteer

Jason

LLS Volunteer

Denisse

LLS Volunteer

Snapshot of Sudha, who is LLS volunteer

Sudha

LLS Volunteer

Andrew Rich running at the racing event, Team in Training paticipant

Team In Training Participant

Team In Training Participant

Volunteer

Volunteer

The Leukemia & Lymphoma Society (LLS) is now Blood Cancer United. Learn more.