
Get our free fact sheet, Oral Treatment Adherance
This fact sheet provides information about oral treatment adherence, including tips and resources to help you remember to take your medications.
Download or order up to 50 copies today.
Chemotherapy is the use of potent drugs or chemicals, often in combinations or intervals, to kill or damage cancer cells in the body. Chemotherapy drugs are often called anticancer agents. The drugs must be toxic enough to kill leukemic cells, which is why chemotherapy can be hard on your body—the drugs' toxicity can harm your healthy cells as well. However, successful chemotherapy depends on the fact that cancerous cells are more sensitive to the chemicals in the drug than normal cells are.
For information about the drugs listed on this page, visit our cancer drug listing.
The progress in treatment and survival for patients with blood cancers is largely due to the development of chemotherapy drugs over the past 40 years. Today's treatments for leukemia, lymphoma, myeloma, and other types of blood cancers sometimes combine chemotherapy with radiation therapy. Very high dose chemotherapy followed by stem cell transplantation can also be used.
The goal of chemotherapy is to damage or kill cancer cells so there's either no sign of illness (remission) or the disease's progress is slowed. Chemotherapy can produce long-term remission or outright cure for many people, depending on the cancer type and its extent.
How does chemotherapy work?
Normal, healthy cells divide and grow in a controlled pattern. When a healthy cell divides, it replicates itself and produces two cells that are identical. Cancer cells, on the other hand, grow uncontrollably and rapidly with no pattern. When a cancer cell comes into contact with a normal cell, the cancer cell takes over and copies itself many times, overburdening the body with cancer cells.
All chemotherapy drugs interfere with cancer cells' ability to grow or multiply. Different groups of drugs harm cancer cells in different ways. Certain chemotherapy drugs are used only for certain disease cell types—that's why it's essential that the disease be accurately diagnosed.
How are chemotherapy drugs given?
Chemotherapy drugs can sometimes be swallowed in pill, capsule, or liquid form. But in most cases, you'll receive the drugs through a catheter, or central line—a small device that's placed in one of your veins, usually in your upper chest, through a small surgical incision. The catheter can stay in place for weeks or months.
Your doctor or nurse uses the catheter—a thin, flexible tube or intravenous (IV) line—to deliver the drugs directly into your bloodstream. Using a catheter instead of repeatedly inserting an IV needle can help ward off infection and irritation, and may be more comfortable.
Overcoming anxiety about chemotherapy
Having to make choices about chemotherapy and other treatment options can cause a great deal of anxiety. Asking your doctor any questions you have may ease stress and give you some sense of relief in making these choices. In addition, your nurses, social workers, and other health professionals understand the complexity of the emotions and ongoing needs of what you're enduring. They're available to spend time with you, answer questions, lend emotional support, and provide referrals to other useful resources. Blood Cancer United Information Specialists are also available to answer your questions and offer support.
Questions to ask about taking chemotherapy medications at home
You may sometimes be able to take chemotherapy drugs at home. Before starting your regimen, ask your doctor these questions so you thoroughly understand how you're supposed to take the drugs and what to do if problems arise:
- What if I miss a dose?
- What if I vomit immediately after taking my medication?
- Is it safe to drink alcohol during my use of this drug?
- When should I take the medication?
- How should I store it?
- Do I need to take this drug with food?
- When and how should I contact the healthcare team with questions?
- How do I contact a healthcare professional after hours?
Common chemotherapy side effects
The following side effects are common to chemotherapy. You may not experience these side effects, or you may experience different ones. Always talk to your healthcare team about any side effects that you are experiencing, such as:
- Extreme fatigue
- Infections
- Hair loss
- Nausea and vomiting
- Diarrhea
- Heartburn
- Constipation
- Mouth sores
- Aches and pains
- Low blood pressure
- Low levels of red cells, white cells, and platelets in the blood
- Anemia (caused by a low red cell count)
- Rash
Learn more about chemotherapy side effects and how to manage them.
Get our Health Manager App!

Download the Blood Cancer United Health Manager App to track your health during treatment
Manage your health by tracking your side effects, medication, food and hydration, questions for your doctor, grocery lists, and more.Available in the Apple Store and Google Play.
Get free, one-on-one support
Call, email, or chat with a member of our highly trained support team.
Blood Cancer United resources
Find free, specialized guidance and information for every type of blood cancer, request financial support, find emotional support, and connect with other members of the blood cancer community.