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Denosumab

Names

Xgeva® Denosumab

Indications and usage

Denosumab is FDA approved for  the prevention of skeletal-related events in patients with multiple myeloma.


 

Side effects needing medical attention

For multiple myeloma patients receiving denosumab, the most common adverse reactions were diarrhea, nausea, anemia, back pain, thrombocytopenia, peripheral edema, hypocalcemia, upper respiratory tract infection, rash, and headache.

The most common serious adverse reaction was pneumonia.

Side effects needing medical attention after stopping this medication

The most common adverse reaction resulting in discontinuation of denosumab was osteonecrosis of the jaw.


 

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