1629 results for Leukemia
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Targeting Leukemia Stem Cells in the Clinical Setting: The Development of A Comprehensive Program
My focus is to develop a program in which novel therapies targeting leukemia stem cells (LSCs) are tested in clinical trials. This is achieved via par…
Targeting the interplay between signaling and transcriptional dysfunction in myeloid leukemias
Our research program is focused on understanding the intersection between signaling and transcriptional dysfunction in myeloid leukemias. We leverage …
Suggested Reading - My Journey with Leukemia: The Power of Family, Faith, and Humor
My Journey with Leukemia: The Power of Family, Faith, and Humor By Jennifer Venegas Published by Outskirts Press, 2018, 175 pages ISBN: 978-1-4787-…
Novel targeted therapies for acute myeloid leukaemia and multiple myeloma
Outcomes for acute myeloid leukemia (AML) and multiple myeloma (MM) patients remain inadequate and new treatment options to combat resistance against …
The Leukemia & Lymphoma Society® is now Blood Cancer United®
Today, The Leukemia & Lymphoma Society—now Blood Cancer United—unveiled its first national advertising campaign in more than a decade.
News Release
FDA Approves New Formulation of Important Childhood Leukemia Drug
The U.S. Food and Drug Administration yesterday approved nelarabine injection, a critical treatment for T-cell acute lymphoblastic leukemia (T-ALL), a…
Blood Cancer
Studying the biology and therapeutic vulnerabilities of leukemia stem cells using AML-iPSCs
Acute myeloid leukemia (AML) is an aggressive blood cancer that still lacks effective therapies. Our goal is to identify therapeutic vulnerabilities f…
Detection and Targeting of Enzymatic Base Editing Deregulation in Leukemia Stem Cells
Dr. Jamieson is examining the role of two enzymes (APOBEC3 and ADAR1) known to mutate DNA and RNA, and their role in acute myeloid leukemia (AML) and …
Investigating the dependency for protein synthesis in Venetoclax/Azacitidine-resistant acute myeloid leukemia
Relapsed and/or refractory acute myeloid leukemia (AML) display resistance to Venetoclax and Azacitidine (Ven/Aza) with approximately one third of pat…
Cardioprotective Strategies and Cardiotoxicity Prediction in Children with Acute Myeloid Leukemia
We seek to reduce the adverse cardiac effects of chemotherapy in pediatric AML patients. We are assessing markers of heart function and injury to comp…
Development of peptide-drug conjugates for the treatment of Chronic Myelomonocytic Leukaemia (CMML)
We are aiming to bring a new treatment option to patients with chronic myelomonocytic leukemia (CMML) by utilising CCL2-drug conjugates that specifica…
Epigenetic heterogeneity in age-related clonal hematopoiesis and acute myeloid leukemia
Our focus is to unravel how clonal hematopoiesis (CH) progresses to leukemia. We will investigate how epigenetic heterogeneity affects Tet2-mutant hem…
Lower Dose Mitoxantrone for Venetoclax Resistant Acute Myeloid Leukemia
Venetoclax-based regimens are the standard of care for many patients with acute myeloid leukemia (AML) and are highly active therapeutic strategies fo…
Synergistic targeting of metabolic and epigenetic vulnerabilities in leukemia stem cells
Our lab is focused on identifying unique features that distinguishes acute myeloid leukemia (AML) stem cells from normal blood-forming stem cells. The…
211Astatine-CD123 Radioimmunotherapy for Cancer (Stem) Cell-Directed Treatment of Acute Leukemia
Because acute leukemias are very sensitive to radiation, radioisotopes are ideal payloads to arm antibodies against these difficult-to-cure, aggressiv…
LYMPHOMA: WHAT MAKES THIS BLOOD CANCER SO DIFFERENT?
September is Blood Cancer Awareness Month and The Leukemia & Lymphoma Society (LLS) is increasing awareness about the urgency to find cures for blood …
Chronic Lymphocytic Leukemia (CLL) Diagnosis
An accurate diagnosis for CLL is important in order to estimate the disease’s progression and determine the appropriate treatment.
Living With Chronic Lymphocytic Leukemia (CLL)
Topics CoveredWe invite you to learn more about:Treatment goals for a chronic diseaseNew and emerging therapies for CLLSide-effects managementThe impo…