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Targeting the pathogenic 'fire triangle' of inflammation, metabolism and mutations in myeloid leukemogenesis

My lab is focused on understanding the pathogenic interplay between oncogenic mutations, chronic inflammation and aberrant metabolism as a driver of t…

Investigating the role of preleukemia duration and clonal burden in progression to AML

The development of acute myeloid leukemia (AML) is preceded by a “preleukemic” phase in which mutated hematopoietic stem cells expand due to a fitness…

Targeting GCK as a novel and selective therapeutic strategy against RAS mutated Multiple Myeloma

RAS/MAPK mutations are the key drivers in MM, which occurs in % of newly diagnosed and higher in relapsed MM patients. However, RAS remains undruggabl…

Suggested Reading - Faith, Strength, and Courage: A Memoir of Overcoming Adversity & Embracing Life’s Journey

"Faith, Strength, and Courage" is a compelling memoir by Gregory O. Proctor that explores his battle with multiple myeloma. It highlights the power of…

Suggested Reading - Living Medicine: Don Thomas, Marrow Transplantation, and the Cell Therapy Revolution

Living Medicine is the story of Nobel Prize winner Dr. E Donnall Thomas and the development of human marrow transplantation, a therapy now used to tre…

Genomic and epigenomic interactions of complex structural variants affecting outcome in multiple myeloma

Multiple myeloma is characterized by severe changes in chromosomes that result in gains or losses of genetic material. Several key events disrupt the …

Suggested Reading - Childhood Leukemia Guide for Families, Friends and Caregivers, 5th ed.

This most complete parent guide provides accurate and understandable medical information about leukemia and the various treatment options, as well as …

LLS and 30 patient organizations take action to protect patients from substandard insurance

Health insurance is supposed to protect patients when they need help the most. When it works for patients the way it’s supposed to, it keeps their cos…

Exploiting metabolic dependencies, tumor plasticity and their consequences for drug response of HCL

We have long standing experience in the field of HCL research. The aim of this research proposal is to characterize HCL on single cell level across mu…

Promising Preclinical Combinations of AFM13 and Natural Killer Cells Presented at SITC

Heidelberg, Germany, November , - Affimed N.V. (Nasdaq: AFMD), a company committed to giving patients back their innate ability to fight cancer, an…

The Gift of Time: Giving More Moments to Blood Cancer Patients

As we transition from one year to the next, we often reflect on milestones achieved, challenges faced, and moments shared with those we love. It’s a t…

Hematopoietic Cell Transplantation as Treatment for Blood Cancers: The Team Approach

Let’s Talk About CAR T-Cell Therapy as a Treatment Option: Blood Cancers

Maintaining mental wellbeing following a blood cancer diagnosis: A guide for young adults

Mental health, like physical health, is important to your overall wellbeing. 

New Rule Could Strip Health Coverage From Cancer Patients Undergoing Treatment

WASHINGTON, June , – Today, the Centers for Medicare & Medicaid Services (CMS) issued a new interim final rule on the implementation of Medicaid work…

Senate Health Bill Puts Cancer Care Out of Reach for Many

Patients Would Face New Financial Barriers to TreatmentRye Brook, N.Y. (June , ) – The Senate’s Better Care Reconciliation Act would exacerbate the f…

LLS Announces Expansion of Precision Medicine Approach to Fight Blood Cancer

Rye Brook, NY (July , ) – The Leukemia & Lymphoma Society (LLS) today announced the expansion of its groundbreaking precision medicine Beat AML® Maste…

LLS Investment Pays Off: FDA Approves Immunotherapy for Blood Cancer Patients

Rye Brook, N.Y. (August , ) – Today heralds a new era in cancer treatment with the U.S. Food and Drug Administration (FDA) approval of a new, gene th…

LLS Investment Pays Off: FDA Approves Immunotherapy for Blood Cancer Patients

August commemorated a new era in cancer treatment with the U.S. Food and Drug Administration (FDA) approval of a new, gene therapy that reprograms a…

John Quinones Appears with Blood Cancer Survivors in PSA for LLS

Rye Brook, NY, (December , ) --“If you had a chance to support research that is saving lives…What would you do?” asks John Quinones in a new public se…

LLS Achieves New Milestones in Offensive Against Deadly Blood Cancer AML

Rye Brook, NY (December , ) – The Leukemia & Lymphoma Society® (LLS) continues its assault against acute myeloid leukemia (AML), a deadly blood cancer…

Blood cancer research 2026: Meeting patients where they want to be

Today, Blood Cancer United has two main goals for the research we fund. The search for cures for every form of blood cancer continues. But with so man…

Closer to a Cure Inspires & Educates About Treatment Advances of Blood Cancers

On Tuesday, April , top researchers and clinicians from UCLA joined The Leukemia & Lymphoma Society to share updates on recent innovations in treating…

Winship Cancer Institute of Emory University Joins Beat AML Master Trial

Winship Joins The Leukemia & Lymphoma Society’s Innovative Clinical Trial Emory Winship Cancer Institute is one of the latest major cancer research in…

One Family’s Inspiring Quest to Help Other Families Impacted By Cancer

A nasty cough and extreme fatigue first led Myrna and Lou Binder to bring their - son, Jeff, to the doctor for an examination. But the symptoms persi…