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Aero
At three years old, Aero was a sweet, kind kid. But she was sick often, dealing with colds and fevers for months at a time. Aero’s mom, Michelle, noti…
Dare 2 Dream
Stories
Sarah
I was diagnosed with acute lymphoblastic leukemia ( ALL) in October at the age of . It was a shocking diagnosis. I started feeling bad in September …
Tina
Today I am CELEBRATING!! AHHHHH, SO BLESSED!!! It’s been years since my leukemia diagnosis! I am celebrating because of so many reasons!I am celebrat…
Allison
During the start of the pandemic, my boyfriend began working out from home with all the gyms being closed. While working out, he discovered a lump und…
Personality changes during cancer: What’s happening and how to support
Table of Contents IntroductionWhat are personality changes in cancer patients?How cancer changes a personCan cancer cause mood swings before diagnosis…
Blog
Predisposing factors to leukemia
Table of contents:Predisposing Factors to LeukemiaLeukemia CausesGenetic MutationsIs Leukemia Hereditary?Causes of Leukemia in AdultsCauses of Leukemi…
Avery
When I was a senior in high school, my life changed forever. In my senior year, playing my last season of basketball and gearing up to play college so…
Living with NHL
Jess
Thirteen years ago, my cousin brought me and our family into the The Leukemia & Lymphoma Society (LLS) world. Her friend's dad had lost his battle, an…
Caitlyn
My world started to turn upside down in January of after starting to exercise and trying to lose weight. At first, I thought I had pulled a muscle in…
Patient-Reported Outcomes and Survivorship in Histiocytic Neoplasms
Advances in the treatment of Langerhans cell histiocytosis and disease have led to a growing survivor population; however, there is a lack of informa…
Novel Immunotherapy Combinations in Relapsed, Refractory Mantle Cell Lymphoma
We are evaluating two parallel clinical trials with synergistic immunotherapies in mantle cell lymphoma (MCL), including ) tafasitamab and lenalidomid…
Spatial architecture and malignant cell characterization of nodular lymphocyte-predominant Hodgkin lymphoma
Nodular Hodgkin lymphoma is recognized as a disease entity in a spectrum of related diseases, including rich lymphoma. Although treatments are gene…
Happiness is Camping
To provide children with cancer and their siblings a traditional residential camp experience together with sophisticated medical care for campers both…
Addie
Charles Esten, an actor/musician who plays Deacon Claybourne on the TV show “Nashville,” is this year’s Light The Night Walk National Honorary Chair. …
Identifying Mechanisms of Chemoresistance Induced by MECOM in Primary-Refractory Acute Myeloid Leukemia
Approximately % of Acute Myeloid Leukemia (AML) patients are “” () and fail to go into remission with intensive induction chemotherapy. These patients…
How does loss of chromosome Y perturb blood cell biology and create therapeutic vulnerabilities in acute myeloid leukemia?
Loss of chromosome Y (LOY) is common in acute myeloid leukemia (AML) yet the mechanistic and therapeutic roles of LOY remain largely unexplored. Using…
Leveraging the ubiquitin proteasome system for targeted therapy in Acute Myeloid Leukemia
This research proposal will investigate the role of protein degradation in acute myeloid leukemia (AML). Specifically, we will assess the function of…
Investigating the tumor-unique mannose-lectin interaction for a novel diagnostic, prognostic and therapeutic antibody approach of follicular lymphoma
We have discovered that the tumor cells of the vast majority of follicular lymphoma cases have a unique feature in their major receptor. This is an e…
Understanding the clonal origin, evolution, and progression of myeloid malignancies
The overarching focus of my research is to understand the clonal origin, evolution, and progression of myeloid malignancies and biological and clinica…
Clinical and molecular determinants of CLL eradication with targeted combination therapy
The genomic architecture of residual CLL and molecular determinants of disease progression after targeted combination therapy are unknown. In a phase …
Characterization and Targeting of Tumor-Associated Monocytes/ Macrophages that Limit the Efficacy of PD-1 Blockade in Lymphoma
Inhibition of the exhaustion pathway enables the immune system to attack cancers. blockade is now a standard treatment for relapsed classic Hodgkin …
T-cell immunotherapy for prevention of COVID-19 following bone marrow transplantation
infections may be prolonged in cancer patients and may enable intrahost development of virulent viral variants. Adoptive immunotherapy with has been…
Shining Stars Foundation
To transform lives through outdoor recreational and social programs for children and their families challenged with pediatric cancer or other illness…
David
In November , I’d had a cough for several weeks that wouldn’t go away. Didn’t really think much of it. A buddy of mine and I decided to head to Vegas …
Stories
Cancer Support Community (CSC)
To provide support, education and hope to people affected by cancer; to ensure that all people impacted by cancer are empowered by knowledge, strength…