1714 results for Treatments
Refine Your Search
MULTIlayer Predictive models for relapsed MCL after ibrutinib as first line therapY (MULTIPLY)
The MULTIPLY is a large multi-institutional project aimed at characterization of a variety of clinical predictors, both baseline and at relapse throug…
William
The Leukemia and Lymphoma Society (LLS) holds a special place in my heart. I lost my mother to therapy associated with acute myeloid leukemia (AML) in…
Sabrina
May of 2017, I was diagnosed with Hodgkin’s lymphoma following my 19th birthday. The news of cancer shook my reality as I’d just began establishing my…
Angela
I was diagnosed with chronic lymphocytic leukemia (CLL) in April 2009. I was so devastated. The first thing that got me through was a friend who had j…
A First-in-human Clinical Trial of CD5 knocked-out Chimeric Antigen T Cells for T-cell Lymphomas
This proposal seeks to develop for the first time in humans a novel CD5 knocked out (KO) anti-CD5 chimeric antigen receptor T cell (CART) product for …
Patient Experience Research and Palliative Care Integration in Malignant Hematology
My research aims to improve the patient and caregiver experience of blood cancer care. To achieve this, I conduct trials of integrated palliative care…
Understanding sex differences in myeloid and dendritic differentiation and function to target high-risk leukemias including BPDCN
There are widely recognized but unexplained sex differences in cancer incidence and outcomes, including in blastic plasmacytoid dendritic cell neoplas…
EBV promotes Burkitt's lymphoma progression through microprocessor sequestration.
This proposal aims to understand the molecular mechanisms underlying response to AZA therapy in MDS, as a basis for developing more effective therapie…
Aberrant LZTR1 and RIT1 signaling as a driver of clonal hematopoietic disorders
Our research focuses on a novel mechanism of RAS protein regulation via the protein LZTR1, which is altered in leukemia and hinders the effectiveness …
Novel immunotherapeutic strategies in infants with high risk AML
Treatment of AML in infants is especially challenging given unique genetic make-up of the disease as well as specific susceptibilities of the host. We…
Targeting SF3B1 splicing factor mutant myeloid malignancies through dependency on GPATCH8
Mutations in RNA splicing factors, particularly those involving the core splicing factor SF3B1 are amongst the most common mutations found in myeloid …
Targeting the cell surface U5 snRNP complex as a novel immunotherapy for AML
A major limitation of immunotherapy approaches for AML has been the lack of known targetable cell surface antigens specific to AML cells. This project…
The role of Gasdermin D in the inflammation-driven pathogenesis of myelodysplastic syndromes
We aim to understand the mechanism of how dysregulated Gasdermin D(GSDMD) protein propels the pathogenesis of myelodysplastic syndromes(MDS). With sin…
Strategic combinations to overcome therapeutic resistance and relapse in acute myeloid leukemia
Acute myeloid leukemia (AML) is the most fatal type of leukemia and has a high rate of relapse following current therapies. We have recently uncovered…
Histiocytosis Association
Dedicated to raising awareness about histiocytic disorders, providing educational and emotional support, and funding research leading to better treatm…
Children’s Leukemia Research Association (CLRA)
To support research efforts towards finding the causes and cure for leukemia. Patient Aid Program offers limited funds (up to $3,000 per year) t…
CML Society of Canada
To help reduce suffering and to improve the care and quality of life of CML patients; to provide support, education and information on CML, current an…
The Myelodysplastic Syndromes (MDS) Foundation, Inc.
A multi-disciplinary, international organization devoted to MDS support, research, treatment, and education for patients, caregivers, physicians, nurs…
Dr. Green
Anthony Green, M.D., Ph.D., leads an LLS Specialized Center of Research grant.His work is aimed at understanding at the genomic scale how patients wit…
EBeauty
To provide all women, regardless of economic status, access to wigs in order to restore their self-image and confidence during cancer treatments …
MPN Voice
To provide information, community and advocacy for patients diagnosed with a myeloproliferative neoplasm (such as essential thrombocythemia, polycythe…
Genetics and Genomics: What are They, and Why Are They Important for Cancer Patients?
In this video, you will learn about genetics and genomics, how it is changing the face of cancer treatment, and how you can apply an effective communi…
Crystal
My story starts in early December 2024. I had been getting sick a lot that year, and it finally struck me as odd when it just wouldn’t go away. I had …
Dare 2 Dream
Graft-versus-host disease (GVHD) in children and teens
Graft-versus-host disease (GVHD) is a potentially serious complication of allogeneic stem cell transplantation and reduced-intensity allogeneic stem c…
Support Resources
Graft-versus-host disease (GVHD) in young adults
Graft-versus-host disease (GVHD) is a potentially serious complication of allogeneic stem cell transplantation and reduced-intensity allogeneic stem c…
Support Resources