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Precision Medicine Inhibitor and Immunotherapy Approaches for High-Risk Childhood Leukemias
Dr Tasian’s scientific passion is successful development of precision medicine therapies for childhood leukemia. Her translational laboratory researc…
T-cell immunotherapy for prevention of COVID-19 following bone marrow transplantation
infections may be prolonged in cancer patients and may enable intrahost development of virulent viral variants. Adoptive immunotherapy with has been…
Shining Stars Foundation
To transform lives through outdoor recreational and social programs for children and their families challenged with pediatric cancer or other illness…
Targeting the cell surface U5 snRNP complex as a novel immunotherapy for AML
A major limitation of immunotherapy approaches for AML has been the lack of known targetable cell surface antigens specific to AML cells. This project…
Mantle Cell Lymphoma Video Vignettes for Healthcare Professionals
Developed through a collaboration between The Leukemia & Lymphoma Society & The Association of Cancer Care Centers.This video series provides an overv…
Education Resources
Improving Immunotherapy in Multiple Myeloma Through Innovative Clinical Trials, Real-World Evidence and Correlative Research
The overall focus of my research is improving outcomes with immunotherapy in multiple myeloma. I will accomplish this through ) novel clinical trials…
Impaired dynamic nucleosome remodeling as a leukemogenic mechanism and therapeutic target in AML
The cohesin and BAF complexes are both epigenetic regulators of dynamic chromatin accessibility. Recurrent mutations are observed in proteins of both …
Impact of sublethal radiation dose on tumor response, microenvironment and the immune system
Extremely low dose radiation can improve blood cancer outcomes. But the mechanisms of how sublethal radiation (SRT) affects tumors, the microenvironme…
Epigenetic Mechanisms in Acute Myeloid Leukemia
The goal of this project is to investigate the role of the epigenetic regulator (ENL) and its cancer mutations in acute myeloid leukemia (AML). Our s…
Functionalizing novel PHIP variants in ancestry-specific acute myeloid leukemia
AML risk stratification established by previous studies do not reflect survival outcomes observed in Black patients. Exome sequencing of Black AML pa…
Courageous Parents Network
To orient and empower parents and others caring for children with serious illness, by providing resources and tools that reflect the experience and pe…
Profiling Autoantibody Responses in Acute Myeloid Leukemia (AML) Using REAP and Clinically Annotated Biobank Data
Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by clonal proliferation of abnormal myeloid precursors and poor pro…
CenterWatch
CenterWatch is a source of clinical trials information for patients, caregivers and clinical research professionals. Offers online tools to: …
Precision Medicine For DNMT3A-Mutant T-cell ALL
ALL is an aggressive blood cancer with poor overall survival, high relapse rates, and significant side effects. Using primary patient samples, this …
Investigating and targeting the histone acetylation reader protein ENL in acute leukemias
Leukemia often results from aberrant gene expression caused by epigenetic alterations. Previously we discovered a novel histone acetylation reader dom…
Suggested Reading - Hundred Percent Chance
Hundred Percent Chance: A Memoir is a raw and realistic memoir about a young college student who was diagnosed with Acute Myeloid Leukemia in while h…
Suggested Reading - Cancer Fitness: Exercise Programs for Patients and Survivors
Most cancer patients and survivors think that "rest" will decrease their fatigue and speed their recovery. But in fact, rest can make most patients we…
Predicting progression in myeloproliferative neoplasm patients by reconstructing the history of disease in each patient
Blood cancers called myeloproliferative neoplasms occur when one of the blood stem cells picks up a mutation. Some patients stay in the chronic phase …
Yadien
This is my son Yadien. In January , we were heartbroken at news that this little guy had a mass surrounding his airway heart and lung that was a resu…
GoodRx
To help consumers make better financial choices when filling prescriptions. Provides prices and discounts for prescription drugs at more than…
Suggested Reading - Living Medicine: Don Thomas, Marrow Transplantation, and the Cell Therapy Revolution
Living Medicine is the story of Nobel Prize winner Dr. E Donnall Thomas and the development of human marrow transplantation, a therapy now used to tre…
Ryan
I was diagnosed in October of and started chemotherapy in November, six rounds of at the time was called CHOPR. Oh, and my wife was seven months preg…
Suggested Reading - How Steve Became Ralph
Paperback, pagesHardcover, pages Upon receiving a diagnosis of acute myeloid leukemia, Steve Buechler began telling his story with an email to his n…
Suggested Reading - Hundred Percent Chance
Hundred Percent Chance: A Memoir is a raw and realistic memoir about a young college student who was diagnosed with Acute Myeloid Leukemia in while h…
Richard
I’m a acute myeloid leukemia (AML) survivor. I was diagnosed in and completed the / induction and consolidation then relapsed in and had a full mye…