93 results

Refine Your Search

Headshot of Sarah Tasian, MD who is an award recipient

Sarah Tasian

The Children's Hospital of Philadelphia

Philadelphia, PA
United States

Precision Medicine Inhibitor and Immunotherapy Approaches for High-Risk Childhood Leukemias

Dr Tasian’s scientific passion is successful development of precision medicine therapies for high-risk childhood leukemia. Her translational laboratory research program focuses upon investigation of kinase inhibitors and chimeric antigen receptor (CAR) T cell immunotherapies in childhood ALL and AML using primary patient specimens and patient-derived xenograft models. Through her laboratory and clinical research, she aspires to improve cure rates and minimize toxicities for children with leukemia.

Program: Career Development Program

Project Term: October 1, 2021 - September 30, 2026

Headshot of award recipient Jennifer Trowbridge

Jennifer Trowbridge

The Jackson Laboratory

Bar Harbor, ME
United States

Discovery of Aging-Driven Mechanisms Causing Clonal Hematopoiesis (CH) and its Progression to Hematological Malignancy

My research focuses on why and how risk of acute myeloid leukemia (AML) increases with aging. Studying naturally aged mouse models in combination with mice engineered to express mutations commonly found in human blood stem cells with aging, we are investigating whether certain inflammatory factors that increase during aging increase the risk of leukemia. My goal is to identify biomarkers to assess risk of AML development in aging individuals and define new therapeutic targets to prevent AML.

Program: Career Development Program

Project Term: January 1, 2021 - December 31, 2025

woyach-jennifer_web_sq_dam_file_162356.jpg

Jennifer Woyach

The Ohio State University

Columbus, OH
United States

Overcoming BTK Inhibitor Resistance in Chronic Lymphocytic Leukemia

Coming soon.

Program: Career Development Program

Project Term: April 1, 2021 - March 21, 2026