Martin Carroll

Dr. Carroll is a physician scientist who has been studying leukemia biology for 3 decades.  Until recently Dr. Carroll saw patients with blood cancers at the Philadelphia Veterans Administration Hospital but is now focused solely on research to improve therapy for AML. He has performed that research at the Univeristy of Pennsylvania since 1998.  Dr. Carroll has had a long term commitment to building tools to enhance the understanding of human AML.  These tools have included development of a large tissue bank of patient samples. He has also lead the field in development and application of the study of AML in immunocompromised mice.  His work in xenograft AML models lead to the characterization of chemotherapy resistance as not always being dependent on leukemic stem cells but on metabolic adaptations of the cells to chemotherapy.  Dr. Carroll has been involved in development of previous novel therapies for AML and continues to focus on developing safer and more effective treatments.