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Nataly Cruz-Rodriguez

Photo of Nataly Cruz-Rodriguez

Nataly Cruz-Rodriguez PhD

Regents of the University of Michigan

Ann Arbor, Michigan
United States

I am a Research Scientist in the Deininger Lab at Versiti Blood Research Institute, where my work focuses on leukemia biology—particularly in hematopoietic stem and progenitor cells, mitochondrial function, and the identification of therapeutic targets in hematologic malignancies. I have extensive experience in experimental hematology, including stem cell assays, CRISPR-based genome editing, lentiviral and retroviral modeling, and advanced flow cytometry.

In my current role, I have led projects optimizing functional metabolic assays, such as Seahorse XF analysis, to study mitochondrial bioenergetics in rare stem cell populations. I also work extensively with mouse models of leukemia, including xenografts, and coordinate multi-institutional collaborations for biospecimen acquisition and translational research.

In August 2025, I will transition with the Deininger Lab to the University of Michigan, where I will hold a Research Assistant Professor appointment in the Department of Internal Medicine, Division of Hematology/Oncology. My goal is to continue bridging mechanistic studies with preclinical testing to develop and refine targeted therapies for hematologic malignancies.

The Leukemia & Lymphoma Society (LLS) is now Blood Cancer United. Learn more.