Karim-Jean Armache

Karim-Jean Armache, PhD, is the Laura and Isaac Perlmutter Professor of Biochemistry at NYU Grossman School of Medicine. His research focuses on the mechanistic basis of chromatin regulation, with emphasis on Polycomb and Trithorax group complexes, histone modifications, and the epigenetic control of gene expression. Using integrative approaches spanning structural biology, chemical biology, biochemistry, and cell biology, Dr. Armache’s lab has uncovered fundamental mechanisms of key chromatin‐modifying enzymes and identified new therapeutic opportunities in cancer and developmental disorders.