I am an NIH-funded physician scientist with a scientific and clinical focus on cutaneous lymphomas. We have utilized high-dimensional genomic, epigenetic, and immunological approaches to elucidate the immunobiology of multiple cutaneous T and B cell lymphomas. We utilize a combination of human and mouse models as well as a number of unbiased approaches including whole genome sequencing, bulk and single cell RNA and ATAC-Seq, epigenetic assays such as ATAC-Seq, CUT&RUN, and HiCHIP, as well as spectral flow and multimodal CITE-Seq. These efforts have led to manuscripts published in Nature, Nature Cancer, Cancer Discovery, and Blood. These efforts have been funded by an NIH Director’s New Innovator Award, the Damon Runyon Foundation, the Doris Duke Charitable Foundation, and most recently the Mark Foundation for Cancer Research.
Jaehyuk Choi MD, PhD
The University of Texas Southwestern Medical Center
Dallas, Texas
United States
Project Title
Identification of novel therapeutic strategies for aggressive subtypes of CTCL
Program
Career Development Program