Francesca Del Bufalo

Dr. Del Bufalo is a physician-scientist with interest in childhood malignancies, tumor immunology, immunotherapy and hematopoietic stem cell transplantation. She participated in the preclinical and clinical development of the academic clinical trials with CAR-T cells at OPBG. In particular, she coordinated 2 studies on different CD9-CAR T cell platforms for the treatment of children with relapsed/refractory (r/r) BCP-ALL and the phase I/II study to test GD2-CART01 in children with r/r neuroblastoma. She is the PI of a research project to test donor-derived CAR T cells for the treatment of children/young adults with BCP-ALL. She managed the activation and conduction of the phase I clinical trial on CD7-CART.PEBL for the treatment of children/young adults with r/r T-ALL (PI Prof. Franco Locatelli). She is the new chair of the European iBFM Resistant Disease Committee and President of the Young Investigators Section of the scientific technical committee of the Italian Ministry of Health.