Christopher Oakes

I am an Associate Professor in the Departments of Internal Medicine and Biomedical Informatics at The Ohio State University. My laboratory investigates epigenomic, genetic and other molecular features of a broad range of hematological malignancies, with a focus on B cell lymphoma and acute myeloid leukemia. I explores high-throughput epigenetic and molecular profiling data and combines these analyses with functional evaluation of key genes and molecular pathways. My laboratory is interested in the developmental origins of epigenetic programs in lymphoid and myeloid malignancies and aims to uncover the ontogeny of disease development. Current research focuses on investigating genes that function in establishing aberrant global epigenetic states and landscapes. Beyond fundamental tumor biology, I aims to develop novel molecular diagnostics for clinical stratification and prediction of treatment response, as well as the identification of novel therapeutic targets.