I am a pediatric oncologist and associate professor in the division of bone marrow transplantation at Cincinnati Children’s Hospital Medical Center. I have a clinical and research interest in graft versus host disease because this is the most significant, devastating and life-impacting complication after a bone marrow transplant. I led the study in children of high dose oral vitamin A and showed that when given before starting chemotherapy, vitamin A reduces acute gastrointestinal and chronic graft versus host disease. I am now collaborating with 3 adult BMT programs to try and validate my findings in adult BMT patients as adults tend to have more chronic GVHD than children and I would like to extend this easy and effective strategy to patients of all ages across the US and worldwide.

Pooja Khandelwal MD
Cincinnati Children’s Hospital Medical Center
Cincinnati, Ohio
United States
Project Title
A randomized clinical trial of oral vitamin A to reduce chronic graft versus host disease in BMT
Program
Academic Clinical Trials Program (ACT)